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The C-type lectin-like domain superfamily

Zelensky, Alex; Gready, Jill


The superfamily of proteins containing C-type lectin-like domains (CTLDs) is a large group of extracellular Metazoan proteins with diverse functions. The CTLD structure has a characteristic double-loop ('loop-in-a-loop') stabilized by two highly conserved disulfide bridges located at the bases of the loops, as well as a set of conserved hydrophobic and polar interactions. The second loop, called the long loop region, is structurally and evolutionarily flexible, and is involved in Ca2+-dependent...[Show more]

CollectionsANU Research Publications
Date published: 2005
Type: Journal article
Source: The FEBS Journal
DOI: 10.1111/j.1742-4658.2005.05031.x


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