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The Retinal G Protein-coupled Receptor (RGR) Enhances Isomerohydrolase Activity Independent of Light

Wenzel, Andreas; Oberhauser, Vitus; Pugh, Edward N; Lamb, Trevor; Grimm, Christian; Samardzija, Marijana; Fahl, Edda; Seeliger, Mathius W; Reme, Charlotte E; von Lintig, Johannes


Rod and cone visual pigments use 11-cis-retinal, a vitamin A derivative, as their chromophore. Light isomerizes 11-cis- into all-trans-retinal, triggering a conformational transition of the opsin molecule that initiates phototransduction. After bleaching

CollectionsANU Research Publications
Date published: 2005
Type: Journal article
Source: Journal of Biological Chemistry
DOI: 10.1074/jbc.M503603200


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