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Transport of transforming growth factor-B2 across the blood-brain barrier

McLennan, Ian S; Weible, Michael; Hendry, Ian; Koishi, Kyoko


The blood-brain barrier acts as an interface between the brain and body through a combination of restrictive mechanisms and transport processes. Substances essential for brain function pass through the barrier either by passive diffusion or by active transport. We report here that [ 125I]-transforming growth factor-β2 (TGF-β2) passes through the blood-brain barrier and blood-nerve barriers, after intravenous, intraperitoneal or intramuscular injections. The entry of the [ 125I]-TGF-β2 to the...[Show more]

CollectionsANU Research Publications
Date published: 2005
Type: Journal article
Source: Neuropharmacology
DOI: 10.1016/j.neuropharm.2004.10.005


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