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Hyperpolarization - activated(Ih)currents in auditory brainstem neurons of normal and congenitally deaf mice

Leao, Richardson; Leao (previously Svahn), Katarina; Berntson Eichner, Amy; Walmsley, Bruce


We have investigated the membrane properties of brainstem auditory neurons in a mouse model of congenital deafness (dn/dn). Whole-cell recordings were made from visualized neurons in slices of the medial nucleus of the trapezoid body (MNTB) and anteroventral cochlear nucleus (AVCN). We have recently demonstrated that MNTB neurons in deaf mice are more excitable than in normal mice, due in part to a reduced expression of low-threshold potassium currents. In this study, we have examined the...[Show more]

CollectionsANU Research Publications
Date published: 2005
Type: Journal article
Source: European Journal of Neuroscience
DOI: 10.1111/j.1460-9568.2005.04185.x


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