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Nanostructure of the "protein-nanoparticle corona" an indicator of toxicity?

White, John; Lin, Jhih-Min; Ang, Joo; Campbell, Richard A.; Laux, Valerie; Haertlein, M.; Fragneto, Giovanna


Nanoparticle-protein complexes comprising silica or cadmium sulfide nanoparticles with human proteins have been detected with high sensitivity at the air-water interface using X-ray and neutron reflectivity measurements and ellipsometry. For the interaction between-casein and 8 nm silica particles the sensitivity of the reflectivity signal at the air-water interface has been shown by X-ray reflectmetry to be pico-molar. This high sensitivity results from the nanoparticle-protein interaction...[Show more]

CollectionsANU Research Publications
Date published: 2010
Type: Conference paper
Source: Proceedings of International Conference on Nanoscience and Nanotechnology (ICONN 2010)
DOI: 10.1109/ICONN.2010.6045250


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