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Blood pressure and control of cardiovascular risk

Whitworth, Judith

Description

Two key early 20th century notions, the first the primacy of diastolic pressure in determining risk, and the second that hypertension is a discrete disorder, have proved to be incorrect. We now recognize the primacy of systolic pressure as a risk factor for cardiovascular disease and that hypertension is an arbitrary definition. In the early 21st century, we are moving away from a dichotomous approach to risk classification, and away from notions of hypertension and normotension towards an...[Show more]

dc.contributor.authorWhitworth, Judith
dc.date.accessioned2015-12-13T22:58:00Z
dc.date.available2015-12-13T22:58:00Z
dc.identifier.issn1176-6344
dc.identifier.urihttp://hdl.handle.net/1885/83236
dc.description.abstractTwo key early 20th century notions, the first the primacy of diastolic pressure in determining risk, and the second that hypertension is a discrete disorder, have proved to be incorrect. We now recognize the primacy of systolic pressure as a risk factor for cardiovascular disease and that hypertension is an arbitrary definition. In the early 21st century, we are moving away from a dichotomous approach to risk classification, and away from notions of hypertension and normotension towards an appreciation that blood pressure-related risk is continuous. In parallel, there has been a paradigm shift from a single risk factor approach to comprehensive cardiovascular disease risk prevention. Accordingly, prevention of cardiovascular disease requires a focus on lowering of blood pressure and modification of associated risk factors rather than simply treatment of hypertension. This emphasis is reflected in the World Health Organization (WHO)-International Society of Hypertension (ISH) 2003 statement on management of hypertension.
dc.publisherDove Medical Press Ltd
dc.sourceVascular Health and Risk Management
dc.subjectKeywords: antihypertensive agent; article; blood pressure; cardiovascular disease; drug effect; Europe; human; hypertension; medical society; pathophysiology; practice guideline; risk factor; United States; world health organization; Antihypertensive Agents; Blood
dc.titleBlood pressure and control of cardiovascular risk
dc.typeJournal article
local.description.notesImported from ARIES
local.description.refereedYes
local.identifier.citationvolume1
dc.date.issued2005
local.identifier.absfor110201 - Cardiology (incl. Cardiovascular Diseases)
local.identifier.ariespublicationMigratedxPub11459
local.type.statusPublished Version
local.contributor.affiliationWhitworth, Judith, College of Medicine, Biology and Environment, ANU
local.bibliographicCitation.issue3
local.bibliographicCitation.startpage257
local.bibliographicCitation.lastpage260
dc.date.updated2015-12-12T07:20:21Z
local.identifier.scopusID2-s2.0-33644803813
CollectionsANU Research Publications

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