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Ganglion Blockade does not prevent cortisol-induced hypertension in man

Williamson, Paula M; Tam, Sim Hom; Kelly, John J; Whitworth, Judith


1. The aim of the present study was to assess the effect of ganglion blockade on blood pressure in cortisol treated human subjects. 2. Four healthy male subjects were treated with cortisol 80 mg/day for a 5-day period. Ganglion blockade was achieved by intravenous trimethaphan. 3. Ganglion blockade did not significantly alter blood pressure in the pretreatment phase or on the last day of cortisol treatment. 4. Taken together with our previous observations that sympathetic activity is unaltered...[Show more]

CollectionsANU Research Publications
Date published: 2005
Type: Journal article
Source: Clinical and Experimental Pharmacology and Physiology
DOI: 10.1111/j.1440-1681.2005.04220.x


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