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Proteomic dissection of DNA polymerization

Beck, Jennifer; Urathamakul, Thitima; Watt, Stephen J; Sheil, Margaret; Schaeffer, Patrick; Dixon, Nicholas


DNA polymerases replicate the genome by associating with a range of other proteins that enable rapid, high-fidelity copying of DNA. This complex of proteins and nucleic acids is termed the replisome. Proteins of the replisome must interact with other networks of proteins, such as those involved in DNA repair. Many of the proteins involved in DNA polymerization and the accessory proteins are known, but the array of proteins they interact with, and the spatial and temporal arrangement of these...[Show more]

CollectionsANU Research Publications
Date published: 2006
Type: Journal article
Source: Future Drugs: Expert Review Proteomics
DOI: 10.1586/14789450.3.2.197


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