4-Alkoxycarbonyl- and aminocarbonyl-substituted isoxazoles as masked acrylates and acrylamides in the asymmetric synthesis of Δ 2 -isoxazolines
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Lee, Connie; Herlt, Anthony; Simpson, Gregory Wayne; Willis, Anthony; Easton, Christopher
Description
4-Alkoxycarbonyl and aminocarbonyl-substituted isoxazoles undergo conjugate reduction to give Δ2-isoxazolines on treatment with sodium borohydride and sodium trifluoroacetoxyborohydride, respectively. They are also alkylated at C5 through sonication with
Collections | ANU Research Publications |
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Date published: | 2006 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/83018 |
Source: | Journal of Organic Chemistry |
DOI: | 10.1021/jo0602569 |
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