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4-Alkoxycarbonyl- and aminocarbonyl-substituted isoxazoles as masked acrylates and acrylamides in the asymmetric synthesis of Δ 2 -isoxazolines

Lee, Connie; Herlt, Anthony; Simpson, Gregory Wayne; Willis, Anthony; Easton, Christopher


4-Alkoxycarbonyl and aminocarbonyl-substituted isoxazoles undergo conjugate reduction to give Δ2-isoxazolines on treatment with sodium borohydride and sodium trifluoroacetoxyborohydride, respectively. They are also alkylated at C5 through sonication with

CollectionsANU Research Publications
Date published: 2006
Type: Journal article
Source: Journal of Organic Chemistry
DOI: 10.1021/jo0602569


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