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Speed of Initial Atropinisation in Significant Organophosphorus Pesticide Poisoning - A Systematic Comparison of Recommended Regimens

Eddleston, Michael; Buckley, Nicholas; Checketts, H; Senarathna, Lalith; Mohammed, Fahim; Sheriff, M H Rezvi; Dawson, Andrew


Objective: Early deaths from organophosphorus (OP) pesticide self-poisoning result from respiratory failure and cardiovascular collapse. Therapy requires the urgent use of atropine to reverse cholinergic excess, thereby improving respiratory function, heart rate, and blood pressure. We aimed to assess variation in textbook recommendations for early atropinisation and to see whether this variation affected time to stabilisation using model data from 22 severely poisoned patients seen in a Sri...[Show more]

CollectionsANU Research Publications
Date published: 2004
Type: Journal article
Source: Clinical Toxicology (Taylor & Francis)
DOI: 10.1081/CLT-200035223


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