Drosophila starvin Encodes a Tissue-Specific BAG-Domain Protein Required for Larval Food Uptake
Coulson, Michelle; Robert, Stanley; Saint, Robert
We describe a developmental, genetic, and molecular analysis of the sole Drosophila member of the BAG family of genes, which is implicated in stress response and survival in mammalian cells. We show that the gene, termed starvin (stv), is expressed in a highly tissue-specific manner, accumulating primarily in tendon cells following germ-band retraction and later in somatic muscles and the esophagus during embryonic stage 15. We show that stv expression falls within known tendon and muscle cell...[Show more]
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