Payne, Alan; Willis, Anthony; Sherburn, Michael
Spectacular new atom efficient domino cycloaddition sequences involving dendralene, the simplest cross-conjugated tetraene, are reported. Up to eight stereocenters, three new rings, and six C-C bonds are generated in one synthetic operation. The site selectivity of dienophile addition to cross-conjugated trienes and tetraenes is controlled with a simple Lewis acid.
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