Skip navigation
Skip navigation

Quiescent and activated mouse granulocytes do not express granzyme A and B or perforin: similarities or differences with human polymorphonuclear leukocytes?

Martin, Praxedis; Wallich, Reinhard; Pardo, Julian; Mullbacher, Arno; Munder, Markus; Modolell, Manuel; Simon, Markus M


Polymorphonuclear leukocytes have been shown to use a multitude of effector functions to combat pathogens and tumors, including enzymes, defensins, and toxic products such as oxygen radicals and nitrogen oxides. Recent studies provided evidence for the expression of granzymes (gzms) and perforin (perf) within the cytotoxic arsenal of human neutrophils, the validity of which was questioned by 2 subsequent studies. We have now used cytology, intracellular flow cytometry, enzymatic assays,...[Show more]

CollectionsANU Research Publications
Date published: 2005
Type: Journal article
Source: Blood
DOI: 10.1182/blood-2005-04-1522


File Description SizeFormat Image
01_Martin_Quiescent_and_activated_mouse_2005.pdf766.69 kBAdobe PDF    Request a copy

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  19 May 2020/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator