Skip navigation
Skip navigation

Following directed evolution with crystallography: structural changes observed in changing the substrate specificity of dienelactone hydrolase

Kim, Hye-Kyung; Liu, Jian-Wei; Carr, Paul D; Ollis, David


The enzyme dienelactone hydrolase (DLH) has undergone directed evolution to produce a series of mutant proteins that have enhanced activity towards the non-physiological substrates α-naphthyl acetate and p-nitrophenyl acetate. In terms of steady-state ki

CollectionsANU Research Publications
Date published: 2005
Type: Journal article
Source: Acta Crystallographica Section D: Biological Crystallography
DOI: 10.1107/S0907444905009042


File Description SizeFormat Image
01_Kim_Following_directed_evolution_2005.pdf964.41 kBAdobe PDF    Request a copy

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  20 July 2017/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator