Talaulikar, Girish; Gallagher, Martin; Carney, Gavin; Jadeer, Asad; Falk, Michael C; Hiremagalur, Balaji
Background: The introduction of the immunosuppressant cyclosporine has significantly improved renal transplant survival. It is an expensive drug and generic alternatives may offer cost advantages. However, generic alternatives must be shown to provide equivalent therapeutic efficacy and safety. This study reports our experience of a switch from the microemulsion formulation of cyclosporine, Neoral (Novartis), to the generic equivalent, Cysporin (Mayne Pharma). Method: A two-period,...[Show more]
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