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A cytochrome P450 serves as an unexpected terpene cyclase during fungal meroterpenoid biosynthesis

Chooi, Yit-Heng; Hong, Young J; Cacho, Ralph A; Tantillo, Dean J; Tang, Yi

Description

Viridicatumtoxin (1) is a tetracycline-like fungal meroterpenoid with a unique, fused spirobicyclic ring system. Puzzlingly, no dedicated terpene cyclase is found in the gene cluster identified in Penicillium aethiopicum. Cytochrome P450 enzymes VrtE and

CollectionsANU Research Publications
Date published: 2013
Type: Journal article
URI: http://hdl.handle.net/1885/81539
Source: Journal of the American Chemical Society
DOI: 10.1021/ja408966t

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