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Relationship of homocysteine, folic acid and vitamin B12 with depression in middleaged community sample

Sachdev, Perminder Singh; Parslow, Ruth; Lux, Ora; Salonikas, Chris; Wen, Wei; Naidoo, Daya; Christensen, Helen; Jorm, Anthony F


Background. Case control studies have supported a relationship between low folic acid and vitamin B12 and high homocysteine levels as possible predictors of depression. The results from epidemiological studies are mixed and largely from elderly populations. Method. A random subsample of 412 persons aged 60-64 years from a larger community sample underwent psychiatric and physical assessments, and brain MRI scans. Subjects were assessed using the PRIME-MD Patient Health Questionnaire for...[Show more]

CollectionsANU Research Publications
Date published: 2005
Type: Journal article
Source: Psychological Medicine
DOI: 10.1017/S0033291704003721


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