Opioids inhibit lateral amygdala pyramidal neurons by enhancing a dendritic potassium current
Pyramidal neurons in the lateral amygdala discharge trains of action potentials that show marked spike frequency adaptation, which is primarily mediated by activation of a slow calcium-activated potassium current. We show here that these neurons also express an α-dendrotoxin- and tityustoxin-Kα-sensitive voltage-dependent potassium current that plays a key role in the control of spike discharge frequency. This current is selectively targeted to the primary apical dendrite of these neurons....[Show more]
|Collections||ANU Research Publications|
|Source:||Journal of Neuroscience|
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