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Presynaptic plasticity at two giant auditory synapses in normal and deaf mice

Oleskevich, Sharon; Youssoufian, Monique; Walmsley, Bruce


Large calyceal synapses are often regarded as simple relay points, built for high-fidelity and high-frequency synaptic transmission and a minimal requirement for synaptic plasticity, but this view is oversimplified. Calyceal synapses can exhibit surprising activity-dependent developmental plasticity. Here we compare basal synaptic transmission and activity-dependent plasticity at two stereotypical calyceal synapses in the auditory pathway, the endbulb and the calyx of Held. Basal synaptic...[Show more]

CollectionsANU Research Publications
Date published: 2004
Type: Journal article
Source: Journal of Physiology
DOI: 10.1113/jphysiol.2004.066662


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