Skip navigation
Skip navigation

Adenosine triphosphate acts as both a competitive antagonist and a positive allosteric modulator at recombinant N-Methyl-D-aspartate receptors

Kloda, Anna; Clements, John D; Lewis, Richard J; Adams, David

Description

ATP and glutamate are fast excitatory neurotransmitters in the central nervous system acting primarily on ionotropic P2X and glutamate [N-methyl-D-aspartate (NMDA) and non-NMDA] receptors, respectively. Both neurotransmitters regulate synaptic plasticity

dc.contributor.authorKloda, Anna
dc.contributor.authorClements, John D
dc.contributor.authorLewis, Richard J
dc.contributor.authorAdams, David
dc.date.accessioned2015-12-13T22:50:58Z
dc.date.available2015-12-13T22:50:58Z
dc.identifier.issn0026-895X
dc.identifier.urihttp://hdl.handle.net/1885/81051
dc.description.abstractATP and glutamate are fast excitatory neurotransmitters in the central nervous system acting primarily on ionotropic P2X and glutamate [N-methyl-D-aspartate (NMDA) and non-NMDA] receptors, respectively. Both neurotransmitters regulate synaptic plasticity
dc.publisherAmerican Society for Pharmacology and Experimental Therapeutics
dc.sourceMolecular Pharmacology
dc.subjectKeywords: adenosine diphosphate; adenosine triphosphate; cytidine triphosphate; glutamic acid; guanosine triphosphate; n methyl dextro aspartic acid receptor; neurotransmitter; purine P2X receptor; uridine triphosphate; agonist; allosterism; animal cell; article; b
dc.titleAdenosine triphosphate acts as both a competitive antagonist and a positive allosteric modulator at recombinant N-Methyl-D-aspartate receptors
dc.typeJournal article
local.description.notesImported from ARIES
local.description.refereedYes
local.identifier.citationvolume65
dc.date.issued2004
local.identifier.absfor110902 - Cellular Nervous System
local.identifier.ariespublicationMigratedxPub9380
local.type.statusPublished Version
local.contributor.affiliationKloda, Anna, University of Queensland
local.contributor.affiliationClements, John D, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationLewis, Richard J, University of Queensland
local.contributor.affiliationAdams, David, University of Queensland
local.bibliographicCitation.issue6
local.bibliographicCitation.startpage1386
local.bibliographicCitation.lastpage1396
local.identifier.doi10.1124/mol.65.6.1386
dc.date.updated2015-12-11T10:43:09Z
local.identifier.scopusID2-s2.0-2442702848
CollectionsANU Research Publications

Download

There are no files associated with this item.


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  19 May 2020/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator