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Adenosine triphosphate acts as both a competitive antagonist and a positive allosteric modulator at recombinant N-Methyl-D-aspartate receptors

Kloda, Anna; Clements, John D; Lewis, Richard J; Adams, David

Description

ATP and glutamate are fast excitatory neurotransmitters in the central nervous system acting primarily on ionotropic P2X and glutamate [N-methyl-D-aspartate (NMDA) and non-NMDA] receptors, respectively. Both neurotransmitters regulate synaptic plasticity

CollectionsANU Research Publications
Date published: 2004
Type: Journal article
URI: http://hdl.handle.net/1885/81051
Source: Molecular Pharmacology
DOI: 10.1124/mol.65.6.1386

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