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Synthesis of [123l] iodine labelled imidazo [1,2-b] pyridazines as potential probes for the study of peripheral benzodiazepine receptors using SPECT

Katsifis, Andrew; Barlin, Gordon; Mattner, F; Dikic, Branko


The pyridazines 3-acetamidomethyl-6-chloro-2-(4′-iodophenyl) imidazo[1,2-b]pyridazine 1 (IC50 = 1.6 nM) and 3-benzanfidomethyl-6- iodo-2-(4′-t-butylphenyl)imidazo[1,2-b] pyridazine 2 (IC50 = 4.2 nM), are high affinity and selective ligands for the Per

CollectionsANU Research Publications
Date published: 2004
Type: Journal article
Source: Radiochimica Acta
DOI: 10.1524/ract.92.4.305.35581


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