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Enhanced cellular immunity in macaques following a novel peptide immunotherapy

Chea, Socheata; Dale, C Jane; De Rose, Robert; Ramshaw, Ian; Kent, Stephen J

Description

Advances in treating and preventing AIDS depend on understanding how human immunodeficiency virus (HIV) is eliminated in vivo and on the manipulation of elective immune responses to HIV. During the development of assays quantifying the elimination of fluorescent autologous cells coated with overlapping 15-mer simian immunodeficiency virus (SIV) or HIV-1 peptides, we made a remarkable observation: the reinfusion of macaque peripheral blood mononuclear cells, or even whole blood, pulsed with SIV...[Show more]

CollectionsANU Research Publications
Date published: 2005
Type: Journal article
URI: http://hdl.handle.net/1885/80779
Source: Journal of Virology
DOI: 10.1128/JVI.79.6.3748-3757.2005

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