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Metabolic engineering for the production of natural products

Pickens, Lauren B; Tang, Yi; Chooi, Yit-Heng


Natural products and their derivatives play an important role in modern healthcare as frontline treatments for many diseases and as inspiration for chemically synthesized therapeutics. With advances in sequencing and recombinant DNA technology, many of the biosynthetic pathways responsible for the production of these chemically complex yet valuable compounds have been elucidated. With an ever-expanding toolkit of biosynthetic components, metabolic engineering is an increasingly powerful method...[Show more]

CollectionsANU Research Publications
Date published: 2011
Type: Journal article
Source: Annual Review of Chemical and Biomolecular Engineering
DOI: 10.1146/annurev-chembioeng-061010-114209


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