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Effect of cyclosporin A on the survival and ultrastructure of Echinococcus granulosus protoscoleces in vitro

Colebrook, A L; Jenkins, David; Jones, M K; Tatarczuch, L; Lightowlers, M W


Surgical treatment of human hydatidsosis involves the use of various scolicidal agents to kill infective Echinococcus granulosus protoscoleces that may disseminate into the peritoneal cavity during surgery and potentially re-infect the patient. Currently, no scolicidal agent is completely effective in killing intracystic protoscoleces in humans. Cyclosporin A (CsA) has previously been found to be lethal for E. granulosus protoscoleces in vitro. In this study, we further assessed the...[Show more]

CollectionsANU Research Publications
Date published: 2004
Type: Journal article
Source: Parasitology
DOI: 10.1017/S0031182004005773


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