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MRI Hyperintensities and Depressive Symptoms in a Community Sample of Individuals 60-64 year olds.

Jorm, Anthony F; De Plater, Gregory; Kumar, Rajeev; Wendler, E; Sachdev, Perminder Singh; Anstey, Kaarin


Objective: Previous studies have found associations of magnetic resonance imaging (MRI) signal hyperintensities with depression in the elderly. The present study investigates the association in a younger community sample (age 60-64 years) of depressed subjects and comparison groups for potential mediating and confounding variables. Method: A subsample of 475 persons 60-64 years of age from a larger community survey underwent brain MRI scans. White matter hyperintensities were quantified by...[Show more]

CollectionsANU Research Publications
Date published: 2005
Type: Journal article
Source: American Journal of Psychiatry
DOI: 10.1176/appi.ajp.162.4.699


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