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Electroretinogram changes associated with retinal upregulation of trophic factors: Observations following optic nerve section

Gargini, Claudia; Bisti, Silvia; Demontis, G; Valter (Valter-Kocsi), Krisztina; Stone, Jonathan; Cervetto, Luigi


The purpose of the present work was to assess whether upregulation of trophic factors and protection from damage induced in the retina by optic nerve section are associated with changes in the flash electroretinogram (ERG). We have examined the ERG in adult pigmented rat at different survival times over a period of 3 months following section of the optic nerve. The a-wave was analyzed using the Lamb-Pugh model and the parameters of best fit were estimated in control animals and at successive...[Show more]

CollectionsANU Research Publications
Date published: 2004
Type: Journal article
Source: Neuroscience
DOI: 10.1016/j.neuroscience.2004.04.028


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