Mixed-lineage-leukemia (MLL) fusion protein collaborates with Ras to induce acute leukemia through aberrant Hox expression and Raf activation
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Altmetric Citations
Ono, R.; Kumagai, H.; Nakajima, H.; Hishiya, A.; Taki, T.; Horikawa, Keisuke; Takatsu, Kiyoshi; Satoh, T.; Hayashi, Y.; Kitamura, T.; Nosaka, T.
Description
Mixed-lineage-leukemia (MLL) fusion oncogenes are closely involved in infant acute leukemia, which is frequently accompanied by mutations or overexpression of FMS-like receptor tyrosine kinase 3 (FLT3). Earlier studies have shown that MLL fusion proteins
Collections | ANU Research Publications |
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Date published: | 2009 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/80331 |
Source: | Leukemia |
DOI: | 10.1038/leu.2009.177 |
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01_Ono_Mixed-lineage-leukemia_(MLL)_2009.pdf | 1.02 MB | Adobe PDF | Request a copy |
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