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Brain-derived neurotrophic factor is expressed in a gradient in the superior colliculus during development of the retinocollicular projection

Marotte, Lauren; Vidovic, Maria; Wheeler, E; Jhaveri, S

Description

Theoretical models of topographic map formation have postulated a gradient of attractant in addition to a gradient of repulsion in the target. In species where many axons grow past their correct positions initially, it has also been argued that a parallel gradient of attractant or branching signal is required to ensure collateral formation at the correct position (O'Leary et al., 1999). Brain-derived neurotrophic factor (BDNF) is a known attractant and promotes branching of retinal axons. We...[Show more]

CollectionsANU Research Publications
Date published: 2004
Type: Journal article
URI: http://hdl.handle.net/1885/80330
Source: European Journal of Neuroscience
DOI: 10.1111/j.1460-9568.2004.03521.x

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