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Screening for differential gene expression during the development of form-deprivation myopia in the chicken

Morgan, Ian; Kucharski, Robert; Krongkaew, N; Firth, Sally I; Megaw, Pamela; Maleszka, Ryszard


Purpose. To use the technique of differential gene display to analyze changes in gene expression that occur during the development of and recovery from form-deprivation myopia. Methods. The differential display-reverse transcriptase-polymerase chain reaction technique was used to detect cDNAs that are differentially expressed after 24 h (including 12 h in the light) after fitting with a diffuser to induce form-deprivation myopia. Messenger RNA levels were determined by quantitative Northern...[Show more]

CollectionsANU Research Publications
Date published: 2004
Type: Journal article
Source: Optometry and Vision Science
DOI: 10.1097/00006324-200402000-00013


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