Gill, Jasmita; Yogavel, Manickam; Kumar, Anuj; Belrhali, Hassan; Jain, S.K.; Rug, Melanie; Brown, Monica; Maier, Alex; Sharma, Amit
Nucleosome assembly proteins (NAPs) are histone chaperones that are essential for the transfer and incorporation of histones into nucleosomes. NAPs participate in assembly and disassembly of nucleosomes and in chromatin structure organization. Human malaria parasite Plasmodium falciparum contains two nucleosome assembly proteins termed PfNapL and PfNapS. To gain structural insights into the mechanism of NAPs, we have determined and analyzed the crystal structure of PfNapL at 2.3 Å resolution....[Show more]
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