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Attention deficit hyperactivity behavioral phenotype dimensions of adults from antioquian families using the Wender-Utah scale -Spanish version [Dimensiones del fenotipo conductual del trastorno por dficit de atencin/hiperactividad en adultos de familia

Trujillo-Orrego, Natalia; Pineda, David A; Arango, Clara P; Puerta, IC; Lopera, Francisco; Aguirre-Acevedo, DC; Hincapié-Henao, Liliana; Pineda-Álvarez, Daniel E; Arcos-Burgos, Mauricio (Oscar); Muenke, Maximilian

Description

Introduction. The Wender-Utah Rating Scale (WURS) has been used for retrospective screening of attention deficit hyperactivity disorders (ADHD) symptoms and its comorbidities. Aim. To establish the ADHD behavioralphenotype dimensions of adults from 140 Antioquian families with genetic segregation for ADHD diagnosis, using the WURS -Spanish version. Subjects and methods. 392 adults from both genders, belonging to nuclear and multigenerational families with one or more ADHD affected members were...[Show more]

dc.contributor.authorTrujillo-Orrego, Natalia
dc.contributor.authorPineda, David A
dc.contributor.authorArango, Clara P
dc.contributor.authorPuerta, IC
dc.contributor.authorLopera, Francisco
dc.contributor.authorAguirre-Acevedo, DC
dc.contributor.authorHincapié-Henao, Liliana
dc.contributor.authorPineda-Álvarez, Daniel E
dc.contributor.authorArcos-Burgos, Mauricio (Oscar)
dc.contributor.authorMuenke, Maximilian
dc.date.accessioned2015-12-13T22:45:40Z
dc.identifier.issn0210-0010
dc.identifier.urihttp://hdl.handle.net/1885/79893
dc.description.abstractIntroduction. The Wender-Utah Rating Scale (WURS) has been used for retrospective screening of attention deficit hyperactivity disorders (ADHD) symptoms and its comorbidities. Aim. To establish the ADHD behavioralphenotype dimensions of adults from 140 Antioquian families with genetic segregation for ADHD diagnosis, using the WURS -Spanish version. Subjects and methods. 392 adults from both genders, belonging to nuclear and multigenerational families with one or more ADHD affected members were selected. The Composite International Diagnostic Interview (CIDI) for mental disorder was administered to establish the gold standard diagnosis of ADHD through the long life. All participants fulfill the WURS. Exploratory and confirmatory factor analyses were done to determine the behavioral dimensions of the ADHD phenotype. Results. A factor structure of four dimensions was derived, measuring behavioral decontrol, hyperactivity, inattention and anxiety, and which explained the 60% of the total variance. Conclusions. The behavioral adult ADHD phenotype in the Antioquian families was conformed by four dimensions, which could be used in heritability and linkage future studies.
dc.publisherViguera Editores
dc.sourceRevista de Neurologia
dc.subjectKeywords: adult; anxiety; article; attention; attention deficit disorder; behavior control; disease classification; family study; female; gene segregation; genetic linkage; gold standard; heritability; human; hyperactivity; interview; major clinical study; male; nu ADHD; Adults; Attention disorder; Behavior; Factor analysis; Hyperactivity; Phenotype; Rating scales; Wender
dc.titleAttention deficit hyperactivity behavioral phenotype dimensions of adults from antioquian families using the Wender-Utah scale -Spanish version [Dimensiones del fenotipo conductual del trastorno por dficit de atencin/hiperactividad en adultos de familia
dc.typeJournal article
local.description.notesImported from ARIES
local.identifier.citationvolume48
dc.date.issued2009
local.identifier.absfor060408 - Genomics
local.identifier.ariespublicationf5625xPUB8256
local.type.statusPublished Version
local.contributor.affiliationTrujillo-Orrego, Natalia, University of Antioquia
local.contributor.affiliationPineda, David A, Neurological Institute of Antioquia
local.contributor.affiliationArango, Clara P, University of Antioquia
local.contributor.affiliationPuerta, IC, University of Antioquia
local.contributor.affiliationLopera, Francisco, Neurological Institute of Antioquia
local.contributor.affiliationAguirre-Acevedo, DC, Neurological Institute of Antioquia
local.contributor.affiliationHincapié-Henao, Liliana, University of Antioquia
local.contributor.affiliationPineda-Álvarez, Daniel E, University of Antioquia
local.contributor.affiliationArcos-Burgos, Mauricio (Oscar), College of Medicine, Biology and Environment, ANU
local.contributor.affiliationMuenke, Maximilian, National Human Genome Research Institute
local.description.embargo2037-12-31
local.bibliographicCitation.issue8
local.bibliographicCitation.startpage400
local.bibliographicCitation.lastpage406
dc.date.updated2016-02-24T09:41:11Z
local.identifier.scopusID2-s2.0-65449176839
CollectionsANU Research Publications

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