Booth, Hilary; Burden, Conrad; Maindonald, John; Santoso, Lucia; Wakefield, Matthew; Wilson, Susan
This article discusses the results in Boys and Henderson (2004, Biometrics 60, 573 581) in which the authors propose a new approach to the classification of genomic DNA into a number of hidden Markov states with a variable order of dependency, potentially allowing for the high-throughput detection of structure within genomic DNA. This article is likely to be an important point of departure for further modeling of this type. We question whether the genome of the bacteriophage lambda is the most...[Show more]
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