Maier, Alex; Baum, Jake; Smith, Brian J.; Conway, David J.; Cowman, Alan F.
Invasion of human erythrocytes by the malaria parasite Plasmodium falciparum utilizes multiple ligand- receptor interactions involving erythrocyte receptors and parasite erythrocyte binding proteins of the Duffy binding-like family. Erythrocyte binding antigen 175 (EBA-175) binds to glycophorin A, the most abundant protein on the human erythrocyte surface and EBA-140 (also known as BAEBL) binds to glycophorin C, while the receptor for EBA-181 (also known as JESEBL) remains unknown. EBA binding...[Show more]
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