An improved open-channel structure of MscL determined from FRET confocal microscopy and simulation
Mechanosensitive channels act as molecular transducers of mechanical force exerted on the membrane of living cells by opening in response to membrane bilayer deformations occurring in physiological processes such as touch, hearing, blood pressure regulation, and osmoregulation. Here, we determine the likely structure of the open state of the mechanosensitive channel of large conductance using a combination of patch clamp, fluorescence resonance energy transfer (FRET) spectroscopy, data from...[Show more]
|Collections||ANU Research Publications|
|Source:||Journal of General Physiology|
|01_Corry_An_improved_open-channel_2010.pdf||3.48 MB||Adobe PDF||Request a copy|
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