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Fine-mapping of muscle weight QTL in LG/J and SM/J intercrosses

Lionikas, Arimantas; Cheng, Riyan; Lim, Jackie E; Palmer, Abraham A; Blizard, David A


Genetic variation plays a substantial role in variation in strength, but the underlying mechanisms remain poorly understood. The objective of the present study was to examine the mechanisms underlying variation in muscle mass, a predictor of strength, between LG/J and SM/J strains, which are the inbred progeny of mice selected, respectively, for high and low body weight. We measured weight of five hindlimb muscles in LG/J and SM/J males and females, in F1 and F2 intercrosses, and in an advanced...[Show more]

CollectionsANU Research Publications
Date published: 2010
Type: Journal article
Source: Physiological Genomics
DOI: 10.1152/physiolgenomics.00100.2010


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