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miR-214 regulates lactoferrin expression and pro-apoptotic function in mammary epithelial cells

Liao, Yalin; Du, Xiaogu; Lonnerdal, Bo

Description

Lactoferrin (Lf) is an abundantly expressed protein in human milk. Lactoferrin exhibits several important biological functions, and its expression is regulated by multiple environmental factors. Cellular endogenous factors, however, have not been extensively studied with regard to lactoferrin gene expression. In this study, we showed that lactoferrin gene expression and function are directly targeted by miR-214 in HC11 and MCF7 cells. In the lactoferrin mRNA 39 untranslated region (UTR) of...[Show more]

CollectionsANU Research Publications
Date published: 2010
Type: Journal article
URI: http://hdl.handle.net/1885/79450
Source: Journal of Nutrition
DOI: 10.3945/jn.110.124289

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