Park, Daniel J; Pask, Andrew J; Huynh, Kim; Harley, Vincent R; Renfree, Marilyn B; Graves, Jennifer
Many or most genes on the mammal Y chromosome evolved a testis-specific function after diverging from an X-borne copy with a general function in both sexes. In marsupial but not eutherian mammals, a testis-specific orthologue (ATRY) of the widely expressed X-borne ATRX gene lies on the Y chromosome. Since mutations in human ATRX cause sex reversal, it is possible that one function of ATRY in marsupials is testicular differentiation. We report here the isolation and sequencing of the tammar...[Show more]
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.