Skip navigation
Skip navigation

Preoptic hypothalamic warming suppresses laryngeal dilator activity during sleep

McGinty, Dennis; Metes, Agnes; Alam, Noor; Megirian, David; Steward, Darya; Szymusiak, Ron

Description

Upper airway dilator activity during sleep appears to be diminished under conditions of enhanced sleep propensity, such as after sleep deprivation, leading to worsening of obstructive sleep apnea (OSA). Non-rapid eye movement (NREM) sleep propensity originates in sleep-active neurons of the preoptic area (POA) of the hypothalamus and is facilitated by activation of POA warm-sensitive neurons (WSNs). We hypothesized that activation of WSNs by local POA warming would inhibit activity of the...[Show more]

CollectionsANU Research Publications
Date published: 2004
Type: Journal article
URI: http://hdl.handle.net/1885/78895
Source: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology
DOI: 10.1152/ajpregu.00296.2003

Download

There are no files associated with this item.


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  20 July 2017/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator