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Museum genomics: Low-cost and high-accuracy genetic data from historical specimens

Rowe, Kevin C.; Singhal, Sonal; MacManes, Matthew D.; Ayroles, Julien F.; Morelli, Toni Lyn; Rubidge, Emily M.; Bi, Ke; Moritz, Craig

Description

Natural history collections are unparalleled repositories of geographical and temporal variation in faunal conditions. Molecular studies offer an opportunity to uncover much of this variation; however, genetic studies of historical museum specimens typically rely on extracting highly degraded and chemically modified DNA samples from skins, skulls or other dried samples. Despite this limitation, obtaining short fragments of DNA sequences using traditional PCR amplification of DNA has been the...[Show more]

CollectionsANU Research Publications
Date published: 2011
Type: Journal article
URI: http://hdl.handle.net/1885/78893
Source: Molecular Ecology Resources
DOI: 10.1111/j.1755-0998.2011.03052.x

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