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Potential cognitive endophenotypes in multigenerational families: Segregating ADHD from a genetic isolate

Arcos-Burgos, Mauricio (Oscar); Muenke, Maximilian; Pineda, David A; Lopera, Francisco; Puerta, IC; Trujillo-Orrego, Natalia; Aguirre-Acevedo, DC; Arango, Clara P; Acosta , MT; Palacio, LG

Description

Endophenotypes are neurobiological markers cosegregating and associated with illness. These biomarkers represent a promising strategy to dissect ADHD biological causes. This study was aimed at contrasting the genetics of neuropsychological tasks for intelligence, attention, memory, visual-motor skills, and executive function in children from multigenerational and extended pedigrees that cluster ADHD in a genetic isolate. In a sample of 288 children and adolescents, 194 (67.4%) ADHD affected and...[Show more]

CollectionsANU Research Publications
Date published: 2011
Type: Journal article
URI: http://hdl.handle.net/1885/78802
Source: Attention Deficit and Hyperactivity Disorders - ADHD
DOI: 10.1007/s12402-011-0061-3

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