From the black widow spider to human behavior: Latrophilins, a relatively unknown class of G protein-coupled receptors, are implicated in psychiatric disorders
Martinez, Ariel F; Muenke, Maximilian; Arcos-Burgos, Mauricio (Oscar)
Description
The findings of a recent study associate LPHN3, a member of the latrophilin family, with an increased risk of developing attention deficit/hyperactivity disorder (ADHD), the most common psychiatric disorder in childhood and adolescence. Latrophilins comprise a new family of G protein-coupled receptors of unknown native physiological function that mediate the neurotoxic effects of α-latrotoxin, a potent toxin found in black widow spider venom. This receptor-toxin interaction has helped to...[Show more]
Collections | ANU Research Publications |
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Date published: | 2011 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/78567 |
Source: | American Journal of Medical Genetics, Part B: Neuropsychiatric |
DOI: | 10.1002/ajmg.b.31137 |
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01_Martinez_From_the_black_widow_spider_to_2011.pdf | 1.61 MB | Adobe PDF | Request a copy |
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