From the black widow spider to human behavior: Latrophilins, a relatively unknown class of G protein-coupled receptors, are implicated in psychiatric disorders
The findings of a recent study associate LPHN3, a member of the latrophilin family, with an increased risk of developing attention deficit/hyperactivity disorder (ADHD), the most common psychiatric disorder in childhood and adolescence. Latrophilins comprise a new family of G protein-coupled receptors of unknown native physiological function that mediate the neurotoxic effects of α-latrotoxin, a potent toxin found in black widow spider venom. This receptor-toxin interaction has helped to...[Show more]
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|Source:||American Journal of Medical Genetics, Part B: Neuropsychiatric|
|01_Martinez_From_the_black_widow_spider_to_2011.pdf||1.61 MB||Adobe PDF||Request a copy|
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