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Effect of high pressure on fully hydrated DPPC and POPC bilayers

Chen, Rong; Poger, David; Mark, Alan E.


Enhanced hydrostatic pressure can induce phase transitions in hydrated lipid bilayers especially those composed of saturated phospholipids. In this work, the phase behavior of fully hydrated DPPC (1,2-dipalmitoyl-sn-glycero-3- phosphocholine) and POPC (2-oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine) bilayers as a function of pressure up to 3000 atm has been examined in atomic detail on time scales of up to 1.0 μs, using the molecular dynamics simulation technique. DPPC bilayers formed a...[Show more]

CollectionsANU Research Publications
Date published: 2011
Type: Journal article
Source: Journal of Physical Chemistry B
DOI: 10.1021/jp110002q


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