Balcerowicz, Martin; Fittinghoff, Kirsten; Wirthmueller, Lennart; Maier, Alex; Fackendahl, Petra; Fiene, Gabriele; Koncz, Csaba; Hoecker, Ute
Summary The COP1/SPA complex acts as an E3 ubiquitin ligase to repress photomorphogenesis by targeting activators of the light response for degradation. Genetic analysis has shown that the four members of the SPA gene family (SPA1-SPA4) have overlapping but distinct functions. In particular, SPA1 and SPA2 differ in that SPA1 encodes a potent repressor in light- and dark-grown seedlings, but SPA2 fully loses its function when seedlings are exposed to light, indicating that SPA2 function is...[Show more]
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