Risk HLA-DQA1 and PLA2R1 alleles in idiopathic membranous nephropathy
BACKGROUND: Idiopathic membranous nephropathy is a major cause of the nephrotic syndrome in adults, but its etiologic basis is not fully understood. We investigated the genetic basis of biopsy-proven cases of idiopathic membranous nephropathy in a white population. METHODS: We performed independent genomewide association studies of single-nucleotide polymorphisms (SNPs) in patients with idiopathic membranous nephropathy from three populations of white ancestry (75 French, 146 Dutch, and 335...[Show more]
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|Source:||New England Journal of Medicine|
|01_Stanescu_Risk_HLA-DQA1_and_PLA2R1_2011.pdf||1.19 MB||Adobe PDF||Request a copy|
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