Prevalence of Mild Cognitive Impairment in 60- 64 year old community Dwelling individuals: The Personality and Total Health through Life 60+ Study
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Kumar, Rajeev; Dear, Keith; Christensen, Helen; Ilschner, Susanne DR; Jorm, Anthony F; Meslin, Chantal; Rosenman, Stephen; Sachdev, Perminder Singh
Description
This epidemiological study aimed at determining the prevalence of mild cognitive impairment (MCI) in 60- to 64-year-old individuals using different diagnostic criteria. Community dwelling individuals (n = 2,551) in the age range of 60-64 years were recruited randomly through the electoral roll. They were screened using the MMSE and a short cognitive battery, and those who screened positive underwent detailed medical and cognitive assessments. Extant MCI-related diagnoses were established by...[Show more]
dc.contributor.author | Kumar, Rajeev | |
---|---|---|
dc.contributor.author | Dear, Keith | |
dc.contributor.author | Christensen, Helen | |
dc.contributor.author | Ilschner, Susanne DR | |
dc.contributor.author | Jorm, Anthony F | |
dc.contributor.author | Meslin, Chantal | |
dc.contributor.author | Rosenman, Stephen | |
dc.contributor.author | Sachdev, Perminder Singh | |
dc.date.accessioned | 2015-12-13T22:41:21Z | |
dc.date.available | 2015-12-13T22:41:21Z | |
dc.identifier.issn | 1420-8008 | |
dc.identifier.uri | http://hdl.handle.net/1885/78461 | |
dc.description.abstract | This epidemiological study aimed at determining the prevalence of mild cognitive impairment (MCI) in 60- to 64-year-old individuals using different diagnostic criteria. Community dwelling individuals (n = 2,551) in the age range of 60-64 years were recruited randomly through the electoral roll. They were screened using the MMSE and a short cognitive battery, and those who screened positive underwent detailed medical and cognitive assessments. Extant MCI-related diagnoses were established by consensus. Predictive regression models on the sub-sample were used to determine population prevalence for the diagnoses. Of the 224 subjects who screened positive for MCI, 112 underwent a detailed assessment and 74% met the criteria for at least one recognised diagnosis of mild cognitive deficit (MCI and related diagnoses). By predictive regression modelling, the prevalence of any MCI diagnosis was 13.7% (95% Cl 9.1-30.2) in the population of 60- to 64-year-olds. The estimated prevalence rates for specific diagnoses were: MCI 3.7%, ageing-associated cognitive decline 3.1%, Clinical Dementia Rating score (0.5) 2.8%, age-associated memory impairment 1%, other cognitive disorders 0.9%, and mild neurocognitive disorder 0.6%. Agreement on 'caseness' between various proposed diagnoses was at best fair and generally poor. Memory and other cognitive problems not meeting the threshold for dementia are relatively common in 60- to 64-year-old individuals living in the community. The prevalence rate varies up to six-fold according to the diagnostic criteria applied, with limited overlap between diagnoses. There is an urgent need for standardization of the criteria. | |
dc.publisher | S Karger AG | |
dc.source | Dementia and Geriatric Cognitive Disorders | |
dc.subject | Keywords: adult; aging; article; cognitive defect; community; controlled study; diagnostic test; disease association; human; major clinical study; personality; prediction; prevalence; priority journal; randomization; rating scale; screening; aged; amnesia; Australi Age-associated memory impairment; Ageing-associated cognitive decline; Clinical Dementia Rating; Mild cognitive impairment; Mild neurocognitive disorder | |
dc.title | Prevalence of Mild Cognitive Impairment in 60- 64 year old community Dwelling individuals: The Personality and Total Health through Life 60+ Study | |
dc.type | Journal article | |
local.description.notes | Imported from ARIES | |
local.description.refereed | Yes | |
local.identifier.citationvolume | 19 | |
dc.date.issued | 2005 | |
local.identifier.absfor | 111714 - Mental Health | |
local.identifier.ariespublication | MigratedxPub7099 | |
local.type.status | Published Version | |
local.contributor.affiliation | Kumar, Rajeev, College of Medicine, Biology and Environment, ANU | |
local.contributor.affiliation | Dear, Keith, College of Medicine, Biology and Environment, ANU | |
local.contributor.affiliation | Christensen, Helen, College of Medicine, Biology and Environment, ANU | |
local.contributor.affiliation | Ilschner, Susanne DR, College of Medicine, Biology and Environment, ANU | |
local.contributor.affiliation | Jorm, Anthony F, College of Medicine, Biology and Environment, ANU | |
local.contributor.affiliation | Meslin, Chantal, College of Medicine, Biology and Environment, ANU | |
local.contributor.affiliation | Rosenman, Stephen, College of Medicine, Biology and Environment, ANU | |
local.contributor.affiliation | Sachdev, Perminder Singh, University of New South Wales (Prince of Wales Hospital) | |
local.bibliographicCitation.issue | 2-3 | |
local.bibliographicCitation.startpage | 67 | |
local.bibliographicCitation.lastpage | 74 | |
local.identifier.doi | 10.1159/000082351 | |
dc.date.updated | 2015-12-11T10:00:51Z | |
local.identifier.scopusID | 2-s2.0-20644445026 | |
Collections | ANU Research Publications |
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