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The Influence of Chiral Auxiliaries and Catalysts on the Selectivity of Intramolecular Conjugate Additions of Pyrrole to N -Tethered Michael Acceptors

Banwell, Martin; Beck, Daniel; Smith, Jason A


A series of pyrroles incorporating N-tethered acrylates and related groups has been prepared and examined for their capacity to undergo intramolecular Michael addition reactions to form, in a diastereo- or enantio-selective fashion, the corresponding 8-substituted tetrahydroindolizidine or homologues thereof.

CollectionsANU Research Publications
Date published: 2004
Type: Journal article
Source: Organic and Biomolecular Chemistry
DOI: 10.1039/b312552a


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