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The antioxidant tempol prevents and partially reverses dexamethasone-induced hypertension in the rat

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Zhang, Yi; Croft, Kevin D; Mori, Trevor A; Schyvens, Chris; McKenzie, Katja; Whitworth, Judith

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Background: Many forms of hypertension are associated with increased oxidative stress. This study investigated the effects of Tempol, a superoxide scavenger, on prevention and reversal of hypertension induced by the synthetic glucocorticoid dexamethasone

dc.contributor.authorZhang, Yi
dc.contributor.authorCroft, Kevin D
dc.contributor.authorMori, Trevor A
dc.contributor.authorSchyvens, Chris
dc.contributor.authorMcKenzie, Katja
dc.contributor.authorWhitworth, Judith
dc.date.accessioned2015-12-13T22:40:22Z
dc.date.available2015-12-13T22:40:22Z
dc.identifier.issn0895-7061
dc.identifier.urihttp://hdl.handle.net/1885/78216
dc.description.abstractBackground: Many forms of hypertension are associated with increased oxidative stress. This study investigated the effects of Tempol, a superoxide scavenger, on prevention and reversal of hypertension induced by the synthetic glucocorticoid dexamethasone
dc.publisherElsevier
dc.sourceAmerican Journal of Hypertension
dc.subjectKeywords: antioxidant; dexamethasone; drinking water; glucocorticoid; isoprostane; tempol; animal experiment; animal model; animal tissue; article; controlled study; hypertension; male; nonhuman; oxidative stress; plasma; priority journal; rat; systolic blood press Dexamethasone; F2-isoprostanes; Hypertension; Oxidative stress; Tempol
dc.titleThe antioxidant tempol prevents and partially reverses dexamethasone-induced hypertension in the rat
dc.typeJournal article
local.description.notesImported from ARIES
local.description.refereedYes
local.identifier.citationvolume17
dc.date.issued2004
local.identifier.absfor110201 - Cardiology (incl. Cardiovascular Diseases)
local.identifier.ariespublicationMigratedxPub6892
local.type.statusPublished Version
local.contributor.affiliationZhang, Yi, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationCroft, Kevin D, University of Western Australia
local.contributor.affiliationMori, Trevor A, University of Western Australia
local.contributor.affiliationSchyvens, Chris, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationMcKenzie, Katja, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationWhitworth, Judith, College of Medicine, Biology and Environment, ANU
local.bibliographicCitation.issue3
local.bibliographicCitation.startpage260
local.bibliographicCitation.lastpage265
local.identifier.doi10.1016/j.amjhyper.2003.11.004
dc.date.updated2015-12-11T09:55:35Z
local.identifier.scopusID2-s2.0-1442348273
CollectionsANU Research Publications

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