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Differential regulation of the Let-7 family of microRNAs in CD4 + T cells alters IL-10 expression

Clancy, Jennifer; Swaminathan, Sanjay; Suzuki, Kazuo; Seddiki, Nabila; Kaplan, Warren; Cowley, Mark J.; Hood, Chantelle; Gelgor, Linda; Cooper, David A; Kelleher, Anthony D

Description

MicroRNAs (miRNAs) are ∼22-nt small RNAs that are important regulators of mRNA turnover and translation. Recent studies have shown the importance of the miRNA pathway in HIV-1 infection, particularly in maintaining latency. Our initial in vitro studies

CollectionsANU Research Publications
Date published: 2012
Type: Journal article
URI: http://hdl.handle.net/1885/78137
Source: Journal of Immunology
DOI: 10.4049/jimmunol.1101196

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