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High-resolution genetic mapping using the mouse Diversity Outbred population

Svenson, Karen L; Gatti, Daniel M.; Valdar, William; Welsh, Catherine E.; Cheng, Riyan; Chesler, Elissa J; Palmer, Abraham A; McMillan, Leonard; Churchill, Gary A


The JAX Diversity Outbred population is a new mouse resource derived from partially inbred Collaborative Cross strains and maintained by randomized outcrossing. As such, it segregates the same allelic variants as the Collaborative Cross but embeds these in a distinct population architecture in which each animal has a high degree of heterozygosity and carries a unique combination of alleles. Phenotypic diversity is striking and often divergent from phenotypes seen in the founder strains of the...[Show more]

CollectionsANU Research Publications
Date published: 2012
Type: Journal article
Source: Genetics (Print) ceased Dec 2009 - don't use
DOI: 10.1534/genetics.111.132597/-/DC1


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